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KMS Membranes: Cost-effectively Separating, Purifying, and Concentrating Pharmaceuticals and Their Intermediates Because they withstand acids, caustics, and solvents, KMS SelRO® membranes provide unique separation technologies in the pharmaceutical industry. For some applications, traditional ROMICON® hollow fiber cartridges and spiral wound SPIRAPRO modules provide cost-effective purification and concentration.Concentration of Antibiotics, Pharmaceutical Intermediates, and Peptides Membrane technology can be used to concentrate these important ingredients, while recovering the organic solvents for reuse in manufacturing. One example is the concentration of 6-aminopenicillanic acid (6-APA) and the recovery of the methanol/methylene chloride sovent solution High Pressure Liquid Chromatography (HPLC) Concentration and Solvent Reuse Membranes are used in both the reverse and normal phases of HPLC processing, separating contaminants and concentrating the main fraction. SelRO® Pharmaceutical Applications Clean in Place (CIP) of Fermentation Equipment Cleaning of pharmaceutical fermentation equipment is required to maintain high hygienic standards and ensure proper function of the equipment. The 2% caustic solution can be recovered and reused through membrane recovery. Acids are sometimes used to remove water hardeners from the equipment. The acid can also be reused though membrane recovery. SelRO® Pharmaceutical Applications KMS Product Lines for Pharmaceutical Applications Koch Membrane Systems offers the ROMIPRO® hollow fiber product line, the SPIRAPROTM spiral wound product line and the SelRO® NF and UF Spiral wound elements for separation operations in the pharmaceutical industry. The products are used in pharmaceutical processes such as clarification, desalting, concentration, and buffer ex-change in the manufacture of proteins, enzymes, polypeptides, blood products, antibiotics, etc. Hollow Fiber ROMIPRO® Cartridges The ROMIPRO® hollow fiber product is available in different cartridge dimensions and a wide range of pore sizes, as shown in Tables 1 and 2.
*Some products can be supplied with different fiber diameter. Please check with KMS for specific information. **See Table 2 for further information on MWCO
Spiral Wound SPIRAPROTM Modules The SPIRAPROTM spiral product is available in different dimensions and a wide range of pore sizes, as shown in the tables. Please check with KMS for more details.
Spiral Wound SelRO® Modules
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KMS Membranes for Specialty Applications-More Options to Choose from and and More Process Expertise to Draw From Considering a new System? |
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Koch Membrane Systems, Inc. 850 Main Street, Wilmington, Massachusetts, USA 01887-3388 Telephone: 1-888-677-5624 Telephone: +1-978-694-7000 Fax: +1-978-657-5208 E-mail: info@kochmembrane.com General Conditions & Legal Notice KMS Standard Terms and Conditions of Sale © Copyright 2004-2008 Koch Membrane Systems, Inc. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
